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MYBL1 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P10243 |
|---|---|
| Clone Names | 110726133 |
| Gene ID | 4603 |
|---|---|
| Other Names | Myb-related protein A, A-Myb, Myb-like protein 1, MYBL1, AMYB |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | MYBL1 |
|---|---|
| Synonyms | AMYB |
| Function | Transcription factor that specifically recognizes the sequence 5'-YAAC[GT]G-3' (PubMed:8058310, PubMed:7987850). Acts as a master regulator of male meiosis by promoting expression of piRNAs: activates expression of both piRNA precursor RNAs and expression of protein-coding genes involved in piRNA metabolism (By similarity). The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons, which is essential for the germline integrity (By similarity). Transcriptional activator of SOX30 (By similarity). |
| Cellular Location | Nucleus {ECO:0000250|UniProtKB:P51960}. |
| Tissue Location | Expressed in a variety of lymphoid and solid tumor lines cultured in vitro |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Strong transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Could have a role in the proliferation and/or differentiation of neurogenic, spermatogenic and B-lymphoid cells.
References
Takahashi, T., et al. FEBS Lett. 358(1):89-96(1995)Ma, X.P., et al. Cancer Res. 54(24):6512-6516(1994)Golay, J., et al. Oncogene 9(9):2469-2479(1994)Barletta, C., et al. Cancer Res. 51(14):3821-3824(1991)Nomura, N., et al. Nucleic Acids Res. 16(23):11075-11089(1988)
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