Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
RELT Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q969Z4 |
|---|---|
| Clone Names | 110726185 |
| Gene ID | 84957 |
|---|---|
| Other Names | Tumor necrosis factor receptor superfamily member 19L, Receptor expressed in lymphoid tissues, RELT, TNFRSF19L |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | RELT |
|---|---|
| Synonyms | TNFRSF19L |
| Function | May play a role in apoptosis (PubMed:28688764, PubMed:19969290). Induces activation of MAPK14/p38 and MAPK8/JNK MAPK cascades, when overexpressed (PubMed:16530727). Involved in dental enamel formation (PubMed:30506946). |
| Cellular Location | Cell membrane; Single-pass type I membrane protein Cytoplasm. Cytoplasm, perinuclear region |
| Tissue Location | Spleen, lymph node, brain, breast and peripheral blood leukocytes (at protein level) (PubMed:28688764). Expressed highly in bone marrow and fetal liver. Very low levels in skeletal muscle, testis and colon. Not detected in kidney and pancreas |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is a member of theTNF-receptor superfamily. This receptor is especially abundant inhematologic tissues. It has been shown to activate the NF-kappaBpathway and selectively bind TNF receptor-associated factor 1(TRAF1). This receptor is capable of stimulating T-cellproliferation in the presence of CD3 signaling, which suggests itsregulatory role in immune response. Two alternatively splicedtranscript variants of this gene encoding the same protein havebeen reported.
References
Cusick, J.K., et al. Cell. Immunol. 261(1):1-8(2010)Polek, T.C., et al. Biochem. Biophys. Res. Commun. 349(3):1016-1024(2006)Bossen, C., et al. J. Biol. Chem. 281(20):13964-13971(2006)Cusick, J.K., et al. Biochem. Biophys. Res. Commun. 340(2):535-543(2006)Zhang, Z., et al. Protein Sci. 13(10):2819-2824(2004)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Other Products
Shipping Information
