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RPIA Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P49247 |
|---|---|
| Clone Names | 110726203 |
| Gene ID | 22934 |
|---|---|
| Other Names | Ribose-5-phosphate isomerase, Phosphoriboisomerase, RPIA, RPI |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | RPIA (HGNC:10297) |
|---|---|
| Synonyms | RPI |
| Function | Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate and participates in the first step of the non- oxidative branch of the pentose phosphate pathway. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is an enzyme, whichcatalyzes the reversible conversion between ribose-5-phosphate andribulose-5-phosphate in the pentose-phosphate pathway. This gene ishighly conserved in most organisms. The enzyme plays an essentialrole in the carbohydrate metabolism. Mutations in this gene causeribose 5-phosphate isomerase deficiency. A pseudogene is found onchromosome 18.
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Berry, G.T. J. Inherit. Metab. Dis. 31 (6), 661 (2008) :Wamelink, M.M., et al. J. Inherit. Metab. Dis. 31(6):703-717(2008)
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