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RPL10L Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q96L21 |
|---|---|
| Clone Names | 110726204 |
| Gene ID | 140801 |
|---|---|
| Other Names | 60S ribosomal protein L10-like, RPL10L |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | RPL10L {ECO:0000303|PubMed:12490704, ECO:0000312|HGNC:HGNC:17976} |
|---|---|
| Function | Testis-specific component of the ribosome, which is required for the transition from prophase to metaphase in male meiosis I (By similarity). Compensates for the inactivated X-linked RPL10 paralog during spermatogenesis (PubMed:12490704). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399, PubMed:25901680, PubMed:32669547). The male germ cell-specific ribosome displays a ribosomal polypeptide exit tunnel of distinct size and charge states compared with the classical ribosome (By similarity). It is responsible for regulating the biosynthesis and folding of a subset of male germ-cell-specific proteins that are essential for the formation of sperm (By similarity). |
| Cellular Location | Cytoplasm |
| Tissue Location | Almost testis-specific (PubMed:12490704, PubMed:19333399, PubMed:28502657). Also expressed in pre- and postmenopausal ovary (PubMed:19333399). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a protein sharing sequence similaritywith ribosomal protein L10. It is not currently known whether theencoded protein is a functional ribosomal protein or whether it hasevolved a function that is independent of the ribosome. This geneis intronless.
References
Balasubramanian, S., et al. Genome Biol. 10 (1), R2 (2009) :Uechi, T., et al. Nucleic Acids Res. 30(24):5369-5375(2002)Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000)
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