|Other Names||Sorting nexin-21, Sorting nexin L, SNX-L, SNX21, C20orf161, SNXL|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in several stages of intracellular trafficking.|
|Cellular Location||Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side|
|Tissue Location||Highly expressed in fetus liver, but only weakly expressed in brain, skeleton muscle, smooth muscle, and cardiac muscle, kidney, and adrenal gland|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the sorting nexin family.Members of this family contain a phox (PX) domain, which is aphosphoinositide binding domain, and are involved in intracellulartrafficking. This protein does not contain a coiled coil region,like some family members. The specific function of this protein hasnot been determined. Multiple transcript variants encoding distinctisoforms have been identified for this gene.
Zeng, W., et al. Biochem. Biophys. Res. Commun. 299(4):542-548(2002)Worby, C.A., et al. Nat. Rev. Mol. Cell Biol. 3(12):919-931(2002)Deloukas, P., et al. Nature 414(6866):865-871(2001)Xu, Y., et al. Biochem. J. 360 (PT 3), 513-530 (2001) :Teasdale, R.D., et al. Biochem. J. 358 (PT 1), 7-16 (2001) :
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