|Other Names||Signal recognition particle receptor subunit alpha, SR-alpha, Docking protein alpha, DP-alpha, SRPR|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Component of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system.|
|Cellular Location||Endoplasmic reticulum membrane; Peripheral membrane protein. Note=Thought to be anchored in the membrane through an interaction with SR-beta, which contains a bona fide transmembrane domain|
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Provided below are standard protocols that you may find useful for product applications.
The gene encodes a subunit of the endoplasmic reticulumsignal recognition particle receptor that, in conjunction with thesignal recognition particle, is involved in the targeting andtranslocation of signal sequence tagged secretory and membraneproteins across the endoplasmic reticulum. Alternative splicingresults in multiple transcript variants.
Janin, N., et al. Hum. Genet. 88(5):583-585(1992)Hortsch, M., et al. Biochem. Biophys. Res. Commun. 150(1):111-117(1988)Hortsch, M., et al. Nucleic Acids Res. 16(1):361-362(1988)Tajima, S., et al. J. Cell Biol. 103(4):1167-1178(1986)
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