|Other Names||GTPase Era, mitochondrial, H-ERA, hERA, Conserved ERA-like GTPase, CEGA, ERA-W, ERA-like protein 1, ERAL1, HERA|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3' terminal stem-loop region. May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly.|
|Cellular Location||Mitochondrion matrix. Mitochondrion inner membrane; Peripheral membrane protein. Note=Localizes on the matrix side on the mitochondrial inner membrane|
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Provided below are standard protocols that you may find useful for product applications.
Era is an essential GTPase that is required for proper cell cycle progression and cell division in E. coli. Human homologues have been isolated which have been designated ERAL1A and ERAL1B.
Dennerlein, S., et al. Biochem. J. 430(3):551-558(2010)Hillman, R.T., et al. Genome Biol. 5 (2), R8 (2004) :Akiyama, T., et al. Genes Cells 6(11):987-1001(2001)Britton, R.A., et al. Genomics 67(1):78-82(2000)
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