AIDA Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q96BJ3 |
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Clone Names | 110808069 |
Gene ID | 64853 |
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Other Names | Axin interactor, dorsalization-associated protein, Axin interaction partner and dorsalization antagonist, AIDA, C1orf80 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | AIDA |
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Synonyms | C1orf80 |
Function | Acts as a ventralizing factor during embryogenesis. Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin- independent dorsalization pathway activated by AXIN/JNK-signaling (By similarity). |
Tissue Location | Widely expressed in adult tissues, with highest expression in the heart and skeletal muscle |
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Provided below are standard protocols that you may find useful for product applications.
Background
AIDA acts as a ventralizing factor during embryogenesis. Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling (By similarity).
References
Rui, Y., et al. Dev. Cell 13(2):268-282(2007)
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