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CRISP1 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P54107
Clone Names 110717036
Peptide ID 110717036
Additional Information
Gene ID 167
Other Names Cysteine-rich secretory protein 1, CRISP-1, AEG-like protein, ARP, Acidic epididymal glycoprotein homolog, CRISP1, AEGL1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms AEGL1
Function May have a role in sperm-egg fusion and maturation.
Cellular Location Note=Located in the lumen and epithelium of distal ductus efferentes and epididymal ducts, and on the postacrosomal region of the sperm head
Tissue Location Caput, corpus, and cauda regions of the epididymis, the ductus deferens, sperm and seminal plasma
Research Areas
Citations (0)

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Fertilization consists of a sequence of specific cell-cellinteractions culminating in the fusion of the sperm and egg plasmamembranes. Recognition, binding, and fusion occur through theinteraction of complementary molecules that are localized tospecific domains of the sperm and egg plasma membranes. In thesperm, the postacrosomal region or equatorial segment is involvedin sperm-egg plasma membrane fusion. The protein encoded by thisgene is a member of the cysteine-rich secretory protein (CRISP)family. This protein is expressed in the epididymis, is secretedinto the epididymal lumen, and binds to the postacrosomal region ofthe sperm head where it plays a role at fertilization in sperm-eggfusion through complementary sites localized on the egg surface.Two isoforms are encoded by transcript variants of this gene.


Mungall, A.J., et al. Nature 425(6960):805-811(2003)Evans, J.P. Hum. Reprod. Update 8(4):297-311(2002)Cuasnicu, P.S., et al. Arch. Med. Res. 32(6):614-618(2001)Cohen, D.J., et al. Biol. Reprod. 65(4):1000-1005(2001)Kirchhoff, C. Rev. Reprod. 3(2):86-95(1998)

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$ 80.00
Cat# BP17635b
Availability: In Stock
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