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SLC27A6 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9Y2P4 |
|---|---|
| Clone Names | 100406128 |
| Gene ID | 28965 |
|---|---|
| Other Names | Long-chain fatty acid transport protein 6, FATP-6, Fatty acid transport protein 6, Fatty-acid-coenzyme A ligase, very long-chain 2, Solute carrier family 27 member 6, Very long-chain acyl-CoA synthetase homolog 1, VLCSH1, hVLCS-H1, SLC27A6, ACSVL2, FACVL2, FATP1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | SLC27A6 |
|---|---|
| Synonyms | ACSVL2, FACVL2, FATP6 |
| Function | Mediates the import of long-chain fatty acids (LCFA) into the cell by facilitating their transport at the plasma membrane (PubMed:12556534). Also functions as an acyl-CoA ligase catalyzing the ATP-dependent formation of fatty acyl-CoA using LCFA and very-long- chain fatty acids (VLCFA) as substrates (By similarity). Plays a pivotal role in regulating available LCFA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation such as the heart (PubMed:12556534). |
| Cellular Location | Cell membrane, sarcolemma; Multi-pass membrane protein. Cell membrane {ECO:0000250|UniProtKB:E9Q9W4}; Multi-pass membrane protein. Note=In heart is exclusively located on the sarcolemma in areas juxtaposed with small blood vessels where it colocalizes CD36. |
| Tissue Location | Strongly expressed in heart and localizes to cardiac myocytes (PubMed:12556534). Expressed at moderate levels in placenta, testis, and adrenal glands. Expressed at very low levels in kidney, bladder and uterus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the fatty acid transportprotein family (FATP). FATPs are involved in the uptake oflong-chain fatty acids and have unique expression patterns.Alternatively spliced transcript variants encoding the same proteinhave been found for this gene.
References
Stelzl, U., et al. Cell 122(6):957-968(2005)Gimeno, R.E., et al. J. Biol. Chem. 278(18):16039-16044(2003)Steinberg, S.J., et al. J. Biol. Chem. 275(21):15605-15608(2000)Steinberg, S.J., et al. Mol. Genet. Metab. 68(1):32-42(1999)Watkins, P.A., et al. Prostaglandins Leukot. Essent. Fatty Acids 60 (5-6), 323-328 (1999) :
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