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INF2 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q27J81
Clone Names 110617096
Additional Information
Gene ID 64423
Other Names Inverted formin-2, HBEBP2-binding protein C, INF2, C14orf151, C14orf173
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name INF2
Synonyms C14orf151, C14orf173
Function Severs actin filaments and accelerates their polymerization and depolymerization.
Cellular Location Cytoplasm, perinuclear region
Tissue Location Widely expressed. In the kidney, expression is apparent in podocytes and some tubule cells
Research Areas
Citations (0)
citation

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Background

This gene represents a member of the formin family ofproteins. It is considered a diaphanous formin due to the presenceof a diaphanous inhibitory domain located at the N-terminus of theencoded protein. Studies of a similar mouse protein indicate thatthe protein encoded by this locus may function in polymerizationand depolymerization of actin filaments. Mutations at this locushave been associated with focal segmental glomerulosclerosis 5.

References

Brown, E.J., et al. Nat. Genet. 42(1):72-76(2010)Chhabra, E.S., et al. J. Biol. Chem. 281(36):26754-26767(2006)Bindschadler, M., et al. Proc. Natl. Acad. Sci. U.S.A. 101(41):14685-14686(2004)

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$ 277.78
Cat# BP17660c
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