|Other Names||Taste receptor type 2 member 20, Taste receptor type 2 member 49, T2R49, Taste receptor type 2 member 56, T2R56, TAS2R20, TAS2R49|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).|
|Cellular Location||Membrane; Multi-pass membrane protein.|
|Tissue Location||Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells|
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Provided below are standard protocols that you may find useful for product applications.
Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
Go, Y., et al. Genetics 170(1):313-326(2005)Fischer, A., et al. Mol. Biol. Evol. 22(3):432-436(2005)Zhang, Y., et al. Cell 112(3):293-301(2003)Bufe, B., et al. Nat. Genet. 32(3):397-401(2002)Montmayeur, J.P., et al. Curr. Opin. Neurobiol. 12(4):366-371(2002)
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