CLEC9A Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q6UXN8 |
---|---|
Clone Names | 110729062 |
Peptide ID | 110729062 |
Gene ID | 283420 |
---|---|
Other Names | C-type lectin domain family 9 member A, CLEC9A |
Format | Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | CLEC9A |
---|---|
Function | Functions as an endocytic receptor on a small subset of myeloid cells specialized for the uptake and processing of material from dead cells. Recognizes filamentous form of actin in association with particular actin-binding domains of cytoskeletal proteins, including spectrin, exposed when cell membranes are damaged, and mediate the cross-presentation of dead-cell associated antigens in a Syk-dependent manner. |
Cellular Location | Membrane; Single-pass type II membrane protein |
Tissue Location | In peripheral blood highly restricted on the surface of BDCA31(+) dendritic cells and on a small subset of CD14(+) and CD16(-) monocytes. |

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abgent.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
CLEC9A is a group V C-type lectin-like receptor (CTLR)that functions as an activation receptor and is expressed onmyeloid lineage cells (Huysamen et al., 2008 [PubMed18408006]).
References
Poulin, L.F., et al. J. Exp. Med. 207(6):1261-1271(2010)Sancho, D., et al. Nature 458(7240):899-903(2009)Caminschi, I., et al. Blood 112(8):3264-3273(2008)Huysamen, C., et al. J. Biol. Chem. 283(24):16693-16701(2008)Sancho, D., et al. J. Clin. Invest. 118(6):2098-2110(2008)

If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abgent.com.