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DCTN6 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | O00399 |
|---|---|
| Clone Names | 110729074 |
| Gene ID | 10671 |
|---|---|
| Other Names | Dynactin subunit 6, Dynactin subunit p27, Protein WS-3, DCTN6, WS3 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | DCTN6 (HGNC:16964) |
|---|---|
| Synonyms | WS3 |
| Function | Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules. |
| Cellular Location | Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:D0G6S1}. Chromosome, centromere, kinetochore |
| Tissue Location | Ubiquitous. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene contains an RGD(Arg-Gly-Asp) motif in the N-terminal region, which confersadhesive properties to macromolecular proteins like fibronectin. Itshares a high degree of sequence similarity with the mouse homolog,which has been suggested to play a role in mitochondrialbiogenesis. The exact biological function of this gene is notknown.
References
Lamesch, P., et al. Genomics 89(3):307-315(2007)Parisi, G., et al. FEBS Lett. 562 (1-3), 1-4 (2004) :Eckley, D.M., et al. J. Cell Biol. 147(2):307-320(1999)Murdock, D.G., et al. J. Biol. Chem. 274(20):14429-14433(1999)Ichikawa, K., et al. Gene 189(2):277-287(1997)
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