FIGNL1 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q6PIW4 |
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Clone Names | 110729088 |
Gene ID | 63979 |
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Other Names | Fidgetin-like protein 1, 364-, FIGNL1 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | FIGNL1 |
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Function | Involved in DNA double-strand break (DBS) repair via homologous recombination (HR). Recruited at DSB sites independently of BRCA2, RAD51 and RAD51 paralogs in a H2AX-dependent manner. May regulate osteoblast proliferation and differentiation (PubMed:23754376). May play a role in the control of male meiosis dynamic (By similarity). |
Cellular Location | Nucleus. Cytoplasm {ECO:0000250|UniProtKB:Q8BPY9}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q8BPY9}. Note=Together with RAD51 and a subset of H2A histone proteins, redistributed in discrete nuclear DNA damage- induced foci after ionizing radiation (IR) treatment (PubMed:23754376) |
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Provided below are standard protocols that you may find useful for product applications.
Background
FIGNL1 may regulate osteoblast proliferation and differentiation (By similarity).
References
de Krom, M., et al. Biol. Psychiatry 65(7):625-630(2009)Matsuoka, S., et al. Science 316(5828):1160-1166(2007)
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