|Other Names||Fidgetin-like protein 1, 364-, FIGNL1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Involved in DNA double-strand break (DBS) repair via homologous recombination (HR). Recruited at DSB sites independently of BRCA2, RAD51 and RAD51 paralogs in a H2AX- dependent manner. May regulate osteoblast proliferation and differentiation.|
|Cellular Location||Nucleus. Note=Together with RAD51 and a subset of H2A histone proteins, redistributed in discrete nuclear DNA damage-induced foci after ionizing radiation (IR) treatment|
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Provided below are standard protocols that you may find useful for product applications.
FIGNL1 may regulate osteoblast proliferation and differentiation (By similarity).
de Krom, M., et al. Biol. Psychiatry 65(7):625-630(2009)Matsuoka, S., et al. Science 316(5828):1160-1166(2007)
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