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NKX3-2 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P78367 |
|---|---|
| Clone Names | 110729155 |
| Gene ID | 579 |
|---|---|
| Other Names | Homeobox protein Nkx-32, Bagpipe homeobox protein homolog 1, Homeobox protein NK-3 homolog B, NKX3-2, BAPX1, NKX3B |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | NKX3-2 |
|---|---|
| Synonyms | BAPX1, NKX3B |
| Function | Transcriptional repressor that acts as a negative regulator of chondrocyte maturation. PLays a role in distal stomach development; required for proper antral-pyloric morphogenesis and development of antral-type epithelium. In concert with GSC, defines the structural components of the middle ear; required for tympanic ring and gonium development and in the regulation of the width of the malleus (By similarity). |
| Cellular Location | Nucleus. |
| Tissue Location | Expressed at highest levels in cartilage, bone (osteosarcoma) and gut (small intestine and colon), whereas moderate expression is seen in trachea and brain. Expressed in visceral mesoderm and embryonic skeleton. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the NK family ofhomeobox-containing proteins. The encoded protein may play a rolein skeletal development.
References
Hellemans, J., et al. Am. J. Hum. Genet. 85(6):916-922(2009)Rodrigo, I., et al. Mol. Cell. Biol. 24(7):2757-2766(2004)Tribioli, C., et al. Gene 203(2):225-233(1997)Yoshiura, K.I., et al. Genomics 45(2):425-428(1997)Tribioli, C., et al. Mech. Dev. 65 (1-2), 145-162 (1997) :
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