|Other Names||Homeobox protein Nkx-32, Bagpipe homeobox protein homolog 1, Homeobox protein NK-3 homolog B, NKX3-2, BAPX1, NKX3B|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Transcriptional repressor that acts as a negative regulator of chondrocyte maturation. PLays a role in distal stomach development; required for proper antral-pyloric morphogenesis and development of antral-type epithelium. In concert with GSC, defines the structural components of the middle ear; required for tympanic ring and gonium development and in the regulation of the width of the malleus (By similarity).|
|Tissue Location||Expressed at highest levels in cartilage, bone (osteosarcoma) and gut (small intestine and colon), whereas moderate expression is seen in trachea and brain. Expressed in visceral mesoderm and embryonic skeleton|
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This gene encodes a member of the NK family ofhomeobox-containing proteins. The encoded protein may play a rolein skeletal development.
Hellemans, J., et al. Am. J. Hum. Genet. 85(6):916-922(2009)Rodrigo, I., et al. Mol. Cell. Biol. 24(7):2757-2766(2004)Tribioli, C., et al. Gene 203(2):225-233(1997)Yoshiura, K.I., et al. Genomics 45(2):425-428(1997)Tribioli, C., et al. Mech. Dev. 65 (1-2), 145-162 (1997) :
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