|Other Names||Zinc finger and BTB domain-containing protein 49, Zinc finger protein 509, ZBTB49, ZNF509|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor. Inhibits cell proliferation by activating either CDKN1A/p21 transcription or RB1 transcription.|
|Cellular Location||Isoform 1: Cytoplasm. Nucleus. Note=Predominantly located in the nucleus.|
|Tissue Location||Highly expressed in normal epidermis and in other epithelial tissues, including in colon and lung. Tends to be down-regulated in colon, lung and skin cancer tissues|
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Provided below are standard protocols that you may find useful for product applications.
ZBTB49 may be involved in transcriptional regulation.
Gerhard, D.S., et al. Genome Res. 14 (10B), 2121-2127 (2004) :
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