|Other Names||Polypyrimidine tract-binding protein 3, Regulator of differentiation 1, Rod1, PTBP3, ROD1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||RNA-binding protein that mediates pre-mRNA alternative splicing regulation. Plays a role in the regulation of cell proliferation, differentiation and migration. Positive regulator of EPO-dependent erythropoiesis. Participates in cell differentiation regulation by repressing tissue-specific exons. Promotes FAS exon 6 skipping. Binds RNA, preferentially to both poly(G) and poly(U).|
|Tissue Location||Expressed in several hematopoietic cell lines examined.|
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
ROD1 is a functional homolog of nrd1, an S. pombeRNA-binding protein that suppresses the onset ofdifferentiation.
Rose, J. Phd, et al. Mol. Med. (2010) In press :Sadvakassova, G., et al. J. Cell. Physiol. 220(3):672-679(2009)Yamamoto, H., et al. Mol. Cell. Biol. 19(5):3829-3841(1999)
If you have any additional inquiries please email technical services at email@example.com.