GJC3 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q8NFK1 |
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Clone Names | 110808151 |
Gene ID | 349149 |
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Other Names | Gap junction gamma-3 protein, Connexin-302, Cx302, Connexin-313, Cx313, Gap junction epsilon-1 protein, GJC3, GJE1 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | GJC3 |
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Synonyms | GJE1 |
Function | One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. |
Cellular Location | Cell membrane; Multi-pass membrane protein. Cell junction, gap junction |
Tissue Location | CNS specific. Expression is restricted to brain, spinal cord, and sciatic nerve. According to PubMed:12881038, expression is abundant in skeletal muscle, liver, and heart, and to a minor degree in pancreas and kidney. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a gap junction protein. The encodedprotein, also known as a connexin, plays a role in formation of gapjunctions, which provide direct connections between neighboringcells. Mutations in this gene have been reported to be associatedwith nonsyndromic hearing loss.
References
Yang, J.J., et al. Hum. Genet. 128(3):303-313(2010)Ramchander, P.V., et al. Genet Test Mol Biomarkers 14(4):539-541(2010)Hong, H.M., et al. Hum. Genet. 127(2):191-199(2010)Wang, W.H., et al. Audiol. Neurootol. 15(2):81-87(2010)Sargiannidou, I., et al. Neurobiol. Dis. 30(2):221-233(2008)
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