|Other Names||Leucine-rich repeat-containing protein 29, F-box and leucine-rich repeat protein 9, F-box protein FBL9, F-box/LRR-repeat protein 9, LRRC29, FBL9, FBXL9|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation.|
|Tissue Location||Expressed in heart, kidney, liver, lung and pancreas.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the F-box protein familywhich is characterized by an approximately 40 amino acid motif, theF-box. The F-box proteins constitute one of the four subunits ofubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box),which function in phosphorylation-dependent ubiquitination. TheF-box proteins are divided into 3 classes: Fbws containing WD-40domains, Fbls containing leucine-rich repeats, and Fbxs containingeither different protein-protein interaction modules or norecognizable motifs. The protein encoded by this gene belongs tothe Fbls class and, in addition to an F-box, contains 9 tandemleucine-rich repeats. Two transcript variants encoding the sameprotein have been found for this gene. Other variants may occur,but their full-length natures have not been characterized.
Winston, J.T., et al. Curr. Biol. 9(20):1180-1182(1999)
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