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MSL3 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q8N5Y2
Clone Names 110808191
Peptide ID 110808191
Additional Information
Gene ID 10943
Other Names Male-specific lethal 3 homolog, Male-specific lethal-3 homolog 1, Male-specific lethal-3 protein-like 1, MSL3-like 1, MSL3, MSL3L1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MSL3
Synonyms MSL3L1
Function May be involved in chromatin remodeling and transcriptional regulation. May have a role in X inactivation. Component of the MSL complex which is responsible for the majority of histone H4 acetylation at 'Lys-16' which is implicated in the formation of higher-order chromatin structure. Specifically recognizes histone H4 monomethylated at 'Lys-20' (H4K20Me1) in a DNA-dependent manner and is proposed to be involved in chromosomal targeting of the MSL complex.
Cellular Location Nucleus.
Tissue Location Expressed in many tissues including liver, pancreas, heart, lung, kidney, skeletal muscle, brain, and placenta, with highest expression in skeletal muscle and heart
Research Areas
Citations (0)

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This gene encodes a nuclear protein that is similar to theproduct of the Drosophila male-specific lethal-3 gene. TheDrosophila protein plays a critical role in a dosage-compensationpathway, which equalizes X-linked gene expression in males andfemales. Thus, the human protein is thought to play a similarfunction in chromatin remodeling and transcriptional regulation,and it has been found as part of a complex that is responsible forhistone H4 lysine-16 acetylation. This gene can undergo Xinactivation. Alternative splicing results in multiple transcriptvariants. Related pseudogenes have been identified on chromosomes2, 7 and 8.


Smith, E.R., et al. Mol. Cell. Biol. 25(21):9175-9188(2005)Marin, I., et al. Mol. Biol. Evol. 17(8):1240-1250(2000)Prakash, S.K., et al. Genomics 59(1):77-84(1999)

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$ 80.00
Cat# BP17736a
(40 western blots)
Availability: In Stock
Bulk Size
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