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TCERG1 Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession O14776
Clone Names 80612069
Peptide ID 80612069
Additional Information
Gene ID 10915
Other Names Transcription elongation regulator 1, TATA box-binding protein-associated factor 2S, Transcription factor CA150, TCERG1, CA150, TAF2S
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TCERG1
Synonyms CA150, TAF2S
Function Transcription factor that binds RNA polymerase II and inhibits the elongation of transcripts from target promoters. Regulates transcription elongation in a TATA box-dependent manner. Necessary for TAT-dependent activation of the human immunodeficiency virus type 1 (HIV-1) promoter.
Cellular Location Nucleus
Tissue Location Detected in brain neurons.
Research Areas
Citations (0)

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Background

This gene encodes a nuclear protein that regulatestranscriptional elongation and pre-mRNA splicing. The encodedprotein interacts with the hyperphosphorylated C-terminal domain ofRNA polymerase II via multiple FF domains, and with the pre-mRNAsplicing factor SF1 via a WW domain. Alternative splicing resultsin multiple transcripts variants encoding different isoforms.

References

Sanchez-Alvarez, M., et al. J. Biol. Chem. 285(20):15220-15233(2010)Koskinen, L.L., et al. Tissue Antigens 74(5):408-416(2009)Murphy, J.M., et al. J. Mol. Biol. 393(2):409-424(2009)Lu, M., et al. J. Mol. Biol. 393(2):397-408(2009)Pearson, J.L., et al. J. Biol. Chem. 283(12):7949-7961(2008)

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$ 80.00
Cat# BP17748b
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