|Other Names||Transcription elongation regulator 1, TATA box-binding protein-associated factor 2S, Transcription factor CA150, TCERG1, CA150, TAF2S|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor that binds RNA polymerase II and inhibits the elongation of transcripts from target promoters. Regulates transcription elongation in a TATA box-dependent manner. Necessary for TAT-dependent activation of the human immunodeficiency virus type 1 (HIV-1) promoter.|
|Tissue Location||Detected in brain neurons.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
This gene encodes a nuclear protein that regulatestranscriptional elongation and pre-mRNA splicing. The encodedprotein interacts with the hyperphosphorylated C-terminal domain ofRNA polymerase II via multiple FF domains, and with the pre-mRNAsplicing factor SF1 via a WW domain. Alternative splicing resultsin multiple transcripts variants encoding different isoforms.
Sanchez-Alvarez, M., et al. J. Biol. Chem. 285(20):15220-15233(2010)Koskinen, L.L., et al. Tissue Antigens 74(5):408-416(2009)Murphy, J.M., et al. J. Mol. Biol. 393(2):409-424(2009)Lu, M., et al. J. Mol. Biol. 393(2):397-408(2009)Pearson, J.L., et al. J. Biol. Chem. 283(12):7949-7961(2008)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.