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EFR3B Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9Y2G0
Clone Names 91201183
Peptide ID 91201183
Additional Information
Gene ID 22979
Other Names Protein EFR3 homolog B, EFR3B, KIAA0953
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name EFR3B (HGNC:29155)
Function Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane (PubMed:23229899, PubMed:25608530, PubMed:26571211). The complex acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis (Probable). In the complex, EFR3B probably acts as the membrane-anchoring component (PubMed:23229899). Also involved in responsiveness to G-protein-coupled receptors; it is however unclear whether this role is direct or indirect (PubMed:25380825).
Cellular Location Cell membrane; Lipid-anchor Cytoplasm, cytosol Note=Palmitoylation anchors the protein to the plasma membrane (PubMed:23229899, PubMed:25380825). A small amount is observed in the cytosol (PubMed:25380825).
Research Areas
Citations (0)

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Background

EFR3B belongs to the EFR3 family.

References

Bailey, S.D., et al. Diabetes Care (2010) In press :Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Gudbjartsson, D.F., et al. Nat. Genet. 40(5):609-615(2008)

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$ 80.00
Cat# BP17768a
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