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CELA1 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9UNI1 |
|---|---|
| Clone Names | 100406299 |
| Gene ID | 1990 |
|---|---|
| Other Names | Chymotrypsin-like elastase family member 1, Elastase-1, Pancreatic elastase 1, CELA1, ELA1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | CELA1 |
|---|---|
| Synonyms | ELA1 |
| Function | Serine proteases that hydrolyze many proteins in addition to elastin. |
| Cellular Location | Secreted {ECO:0000250|UniProtKB:P00772}. |
| Tissue Location | Basal layers of epidermis (at protein level). Not expressed in the pancreas. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Elastases form a subfamily of serine proteases thathydrolyze many proteins in addition to elastin. Humans have sixelastase genes which encode the structurally similar proteinselastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases,pancreatic elastase 1 is not expressed in the pancreas. To date,elastase 1 expression has only been detected in skin keratinocytes.Clinical literature that describes human elastase 1 activity in thepancreas or fecal material is actually referring tochymotrypsin-like elastase family, member 3B.
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Roberts, K.E., et al. Gastroenterology 139(1):130-139(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Talas, U., et al. J. Invest. Dermatol. 114(1):165-170(2000)
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