|Other Names||OX-2 membrane glycoprotein, CD200, CD200, MOX1, MOX2|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein|
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The protein encoded by this gene is a type-1 membraneglycoprotein, which contains two immunoglobulin domains, and thusbelongs to the immunoglobulin superfamily. Studies of the relatedgenes in mouse and rat suggest that this gene may regulate myeloidcell activity and delivers an inhibitory signal for the macrophagelineage in diverse tissues. Multiple alternatively splicedtranscript variants that encode different isoforms have been foundfor this gene.
Dorfman, D.M., et al. Am. J. Clin. Pathol. 134(5):726-733(2010)Wong, K.K., et al. J. Leukoc. Biol. 88(2):361-372(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Koning, N., et al. J Innate Immun 2(2):195-200(2010)Rittie, L., et al. Aging Cell 8(6):738-751(2009)
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