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SRGAP1 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q7Z6B7
Clone Names 100603194
Peptide ID 100603194
Additional Information
Gene ID 57522
Other Names SLIT-ROBO Rho GTPase-activating protein 1, srGAP1, Rho GTPase-activating protein 13, SRGAP1, ARHGAP13, KIAA1304
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SRGAP1
Synonyms ARHGAP13, KIAA1304
Function GTPase-activating protein for RhoA and Cdc42 small GTPases. Together with CDC42 seems to be involved in the pathway mediating the repulsive signaling of Robo and Slit proteins in neuronal migration. SLIT2, probably through interaction with ROBO1, increases the interaction of SRGAP1 with ROBO1 and inactivates CDC42.
Tissue Location Expressed in brain, lung, kidney, and testis.
Research Areas
Citations (0)

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Background

GTPase-activating protein for RhoA and Cdc42 small GTPases. Together with CDC42 seems to be involved in the pathway mediating the repulsive signaling of Robo and Slit proteins in neuronal migration. SLIT2, probably through interaction with ROBO1, increases the interaction of SRGAP1 with ROBO1 and inactivates CDC42.

References

Davila, S., et al. Genes Immun. 11(3):232-238(2010)Voss, M., et al. BMC Immunol. 10, 53 (2009) :Olsen, J.V., et al. Cell 127(3):635-648(2006)Olsen, J.V., et al. Cell 127(3):635-648(2006)Barrios-Rodiles, M., et al. Science 307(5715):1621-1625(2005)

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$ 80.00
Cat# BP17794c
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