SIX6 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | O95475 |
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Clone Names | 110617031 |
Gene ID | 4990 |
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Other Names | Homeobox protein SIX6, Homeodomain protein OPTX2, Optic homeobox 2, Sine oculis homeobox homolog 6, SIX6, OPTX2, SIX9 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | SIX6 |
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Synonyms | OPTX2, SIX9 |
Function | May be involved in eye development. |
Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}. |
Tissue Location | Expressed in the developing and adult retina. Also expressed in the hypothalamic and the pituitary regions |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is a homeobox proteinthat is similar to the Drosophila 'sine oculis' gene product. Thisgene is found in a cluster of related genes on chromosome 14 and isthought to be involved in eye development. Defects in this gene area cause of isolated microphthalmia with cataract type 2 (MCOPCT2).
References
Zhang, X., et al. Mol. Vis. 15, 2911-2918 (2009) :Ou, Z., et al. Am. J. Med. Genet. A 146A (19), 2480-2489 (2008) :Hu, S., et al. Biochemistry 47(11):3586-3594(2008)Aijaz, S., et al. Invest. Ophthalmol. Vis. Sci. 45(11):3871-3876(2004)Gallardo, M.E., et al. Am. J. Med. Genet. A 129A (1), 92-94 (2004) :
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