|Other Names||Ras-related protein Rab-39B, RAB39B|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in vesicular trafficking. Plays a role in synapse formation. May regulate the homeostasis of SNCA/alpha- synuclein. Together with PICK1 proposed to ensure selectively GRIA2 exit from the endoplasmic reticulum to the Golgi and to regulate AMPAR compostion at the post-synapses and thus synaptic transmission (By similarity).|
|Cellular Location||Cell membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus Note=Partial colocalization with markers that cycle from the cell surface to the trans-Golgi network.|
|Tissue Location||Highly expressed in the brain.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the Rab family of proteins.Rab proteins are small GTPases that are involved in vesiculartrafficking.
Giannandrea, M., et al. Am. J. Hum. Genet. 86(2):185-195(2010)Ross, M.T., et al. Nature 434(7031):325-337(2005)Cheng, H., et al. Cytogenet. Genome Res. 97 (1-2), 72-75 (2002) :Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000)
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