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NEO1 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q92859
Clone Names 100712132
Peptide ID 100712132
Additional Information
Gene ID 4756
Other Names Neogenin, Immunoglobulin superfamily DCC subclass member 2, NEO1, IGDCC2, NGN
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name NEO1
Synonyms IGDCC2, NGN
Function Multi-functional cell surface receptor regulating cell adhesion in many diverse developmental processes, including neural tube and mammary gland formation, myogenesis and angiogenesis. Receptor for members of the BMP, netrin, and repulsive guidance molecule (RGM) families. Netrin-Neogenin interactions result in a chemoattractive axon guidance response and cell-cell adhesion, the interaction between NEO1/Neogenin and RGMa and RGMb induces a chemorepulsive response.
Cellular Location Cell membrane; Single-pass type I membrane protein
Tissue Location Widely expressed and also in cancer cell lines
Research Areas
Citations (0)

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This gene encodes a cell surface protein that is a memberof the immunoglobulin superfamily. The encoded protein consists offour N-terminal immunoglobulin-like domains, six fibronectin typeIII domains, a transmembrane domain and a C-terminal internaldomain that shares homology with the tumor suppressor candidategene DCC. This protein may be involved in cell growth anddifferentiation and in cell-cell adhesion. Defects in this gene areassociated with cell proliferation in certain cancers. Alternatesplicing results in multiple transcript variants. [provided byRefSeq].


Bradford, D., et al. J. Comp. Neurol. 518(16):3237-3253(2010)Davila, S., et al. Genes Immun. 11(3):232-238(2010)Zhang, A.S., et al. J. Biol. Chem. 284(34):22580-22589(2009)Fujita, Y., et al. Cell Death Differ. 15(10):1593-1608(2008)Zhang, A.S., et al. J. Biol. Chem. 283(25):17494-17502(2008)

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$ 80.00
Cat# BP17802c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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