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ZNF385A Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q96PM9
Clone Names 110717236
Peptide ID 110717236
Additional Information
Gene ID 25946
Other Names Zinc finger protein 385A, Hematopoietic zinc finger protein, Retinal zinc finger protein, ZNF385A, HZF, RZF, ZNF385
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ZNF385A
Synonyms HZF, RZF, ZNF385
Function RNA-binding protein that affects the localization and the translation of a subset of mRNA. May play a role in adipogenesis through binding to the 3'-UTR of CEBPA mRNA and regulation of its translation. Targets ITPR1 mRNA to dendrites in Purkinje cells, and may regulate its activity-dependent translation. With ELAVL1, binds the 3'-UTR of p53/TP53 mRNAs to control their nuclear export induced by CDKN2A. Hence, may regulate p53/TP53 expression and mediate in part the CDKN2A anti- proliferative activity. May also bind CCNB1 mRNA. Alternatively, may also regulate p53/TP53 activity through direct protein-protein interaction. Interacts with p53/TP53 and promotes cell-cycle arrest over apoptosis enhancing preferentially the DNA binding and transactivation of p53/TP53 on cell-cycle arrest target genes over proapoptotic target genes. May also regulate the ubiquitination and stability of CDKN1A promoting DNA damage-induced cell cycle arrest. Also plays a role in megakaryocytes differentiation.
Cellular Location Cytoplasm. Nucleus, nucleolus. Cell projection, dendrite. Note=Detected in dendrites of Purkinje cells and hippocampal neurons.
Tissue Location Expressed predominantly in the retina.
Research Areas
Citations (0)

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Zinc finger proteins, such as ZNF385A, are regulatoryproteins that act as transcription factors, bind single- ordouble-stranded RNA, or interact with other proteins (Sharma etal., 2004 [PubMed 15527981]).


Das, S., et al. Cell 130(4):624-637(2007)Sharma, S., et al. Gene 342(2):219-229(2004)Kimura, Y., et al. J. Exp. Med. 195(7):941-952(2002)Hidaka, M., et al. Mech. Dev. 90(1):3-15(2000)

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$ 80.00
Cat# BP17816a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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