Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
ALX1 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q15699 |
|---|---|
| Clone Names | 110617094 |
| Gene ID | 8092 |
|---|---|
| Other Names | ALX homeobox protein 1, Cartilage homeoprotein 1, CART-1, ALX1, CART1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | ALX1 (HGNC:1494) |
|---|---|
| Function | Sequence-specific DNA-binding transcription factor that binds palindromic sequences within promoters and may activate or repress the transcription of a subset of genes (PubMed:9753625, PubMed:8756334). Most probably regulates the expression of genes involved in the development of mesenchyme-derived craniofacial structures. Early on in development, it plays a role in forebrain mesenchyme survival (PubMed:20451171). May also induce epithelial to mesenchymal transition (EMT) through the expression of SNAI1 (PubMed:23288509). |
| Cellular Location | Nucleus |
| Tissue Location | Cartilage and cervix tissue. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
The specific function of this gene has yet to bedetermined in humans; however, in rodents, it is necessary forsurvival of the forebrain mesenchyme and may also be involved indevelopment of the cervix. Mutations in the mouse gene lead toneural tube defects such as acrania and meroanencephaly. [providedby RefSeq].
References
Uz, E., et al. Am. J. Hum. Genet. 86(5):789-796(2010)Iioka, T., et al. J. Bone Miner. Res. 18(8):1419-1429(2003)Qu, S., et al. Development 126(2):359-369(1999)Cai, R.L. Biochem. Biophys. Res. Commun. 250(2):305-311(1998)Gordon, D.F., et al. DNA Cell Biol. 15(7):531-541(1996)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Other Products
Shipping Information
