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RMND5A Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9H871
Clone Names 110726191
Additional Information
Gene ID 64795
Other Names Protein RMD5 homolog A, RMND5A
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RMND5A
Function Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. MAEA and RMND5A are both required for catalytic activity of the CTLH E3 ubiquitin-protein ligase complex (PubMed:29911972). Catalytic activity of the complex is required for normal cell proliferation (PubMed:29911972). The CTLH E3 ubiquitin- protein ligase complex is not required for the degradation of enzymes involved in gluconeogenesis, such as FBP1 (PubMed:29911972).
Cellular Location Nucleus, nucleoplasm. Cytoplasm
Research Areas
Citations (0)
citation

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Background

RMND5A contains one CTLH domain and one LisH domain. There are two isoforms.

References

Kobayashi, N., et al. Gene 396(2):236-247(2007)Bowzard, J.B., et al. J. Biol. Chem. 282(24):17568-17580(2007)Lamesch, P., et al. Genomics 89(3):307-315(2007)Colland, F., et al. Genome Res. 14(7):1324-1332(2004)

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$ 277.78
Cat# BP17828b
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