|Other Names||Testican-3, SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3, SPOCK3, TICN3|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May participate in diverse steps of neurogenesis. Inhibits the processing of pro-matrix metalloproteinase 2 (MMP-2) by MT1-MMP and MT3-MMP. May interfere with tumor invasion.|
|Cellular Location||Secreted, extracellular space, extracellular matrix|
|Tissue Location||Expressed in brain.|
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Provided below are standard protocols that you may find useful for product applications.
Proteoglycans, which consist of a core protein andcovalently linked glycosaminoglycans, are components of theextracellular matrix. SPOCK3 encodes a member of a novelCa(2+)-binding proteoglycan family.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Kamioka, M., et al. Leuk. Res. 33(7):913-918(2009)Lamesch, P., et al. Genomics 89(3):307-315(2007)Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)Nakada, M., et al. Cancer Res. 61(24):8896-8902(2001)
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