WDR20 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q8TBZ3 |
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Clone Names | 110726274 |
Gene ID | 91833 |
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Other Names | WD repeat-containing protein 20, Protein DMR, WDR20 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | WDR20 |
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Function | Regulator of deubiquitinating complexes. Activates deubiquitinating activity of complexes containing USP12 (PubMed:20147737, PubMed:27373336). Anchors at the base of the ubiquitin-contacting loop of USP12 and remotely modulates the catalytic center of the enzyme (PubMed:27373336). Regulates shuttling of the USP12 deubiquitinase complex between the plasma membrane, cytoplasm and nucleus (PubMed:30466959). |
Cellular Location | Cytoplasm. Nucleus |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a WD repeat-containing protein. Multiplealternatively spliced transcript variants have been found for thisgene, but the full-length nature of some variants has not beendefined.
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Kee, Y., et al. J. Biol. Chem. 285(15):11252-11257(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Olsen, J.V., et al. Cell 127(3):635-648(2006)
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