|Other Names||Embigin, EMB|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Plays a role in the outgrowth of motoneurons and in the formation of neuromuscular junctions. Following muscle denervation, promotes nerve terminal sprouting and the formation of additional acetylcholine receptor clusters at synaptic sites without affecting terminal Schwann cell number or morphology. Delays the retraction of terminal sprouts following re-innervation of denervated endplates. May play a role in targeting the monocarboxylate transporters SLC16A1 and SLC16A7 to the cell membrane (By similarity).|
|Cellular Location||Cell membrane; Single-pass type I membrane protein. Cell junction, synapse. Note=Localizes to the neuromuscular junctions|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a transmembrane glycoprotein that is amember of the immunoglobulin superfamily. The encoded protein maybe involved in cell growth and development by mediatinginteractions between the cell and extracellular matrix. Apseudogene of this gene is found on chromosome 1. [provided byRefSeq].
Guenette, R.S., et al. Dev. Genet. 21(4):268-278(1997)Ray, M.E., et al. Oncogene 12(12):2527-2533(1996)Ozawa, M., et al. J. Biol. Chem. 263(7):3059-3062(1988)
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