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EMB Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q6PCB8 |
|---|---|
| Clone Names | 110729078 |
| Gene ID | 133418 |
|---|---|
| Other Names | Embigin, EMB |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | EMB |
|---|---|
| Function | Plays a role in the outgrowth of motoneurons and in the formation of neuromuscular junctions. Following muscle denervation, promotes nerve terminal sprouting and the formation of additional acetylcholine receptor clusters at synaptic sites without affecting terminal Schwann cell number or morphology. Delays the retraction of terminal sprouts following re-innervation of denervated endplates. May play a role in targeting the monocarboxylate transporters SLC16A1, SLC16A6 and SLC16A7 to the cell membrane (By similarity). |
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:O88775}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:O88775} Synapse {ECO:0000250|UniProtKB:P21995}. Note=Localizes to the neuromuscular junctions. {ECO:0000250|UniProtKB:P21995} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a transmembrane glycoprotein that is amember of the immunoglobulin superfamily. The encoded protein maybe involved in cell growth and development by mediatinginteractions between the cell and extracellular matrix. Apseudogene of this gene is found on chromosome 1. [provided byRefSeq].
References
Guenette, R.S., et al. Dev. Genet. 21(4):268-278(1997)Ray, M.E., et al. Oncogene 12(12):2527-2533(1996)Ozawa, M., et al. J. Biol. Chem. 263(7):3059-3062(1988)
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