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SLC7A14 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q8TBB6 |
|---|---|
| Clone Names | 110808281 |
| Gene ID | 57709 |
|---|---|
| Other Names | Probable cationic amino acid transporter, Solute carrier family 7 member 14, SLC7A14, KIAA1613 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | SLC7A14 {ECO:0000303|PubMed:24670872, ECO:0000312|HGNC:HGNC:29326} |
|---|---|
| Function | Imports 4-aminobutanoate (GABA) into lysosomes. May act as a GABA sensor that regulates mTORC2-dependent INS signaling and gluconeogenesis. The transport mechanism and substrate selectivity remain to be elucidated. |
| Cellular Location | Lysosome membrane; Multi-pass membrane protein. Note=Exhibits a punctated pattern in the cytoplasm, which partially ovelaps with lysosomes. |
| Tissue Location | Expressed in skin fibroblasts. |
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Provided below are standard protocols that you may find useful for product applications.
Background
SLC7A14 (Solute carrier family 7 member 14) is thought to be a cationic amino acid transporter, belonging to the amino acid-polyamine-organocation (APC) superfamily.
References
Rose, J. Phd, et al. Mol. Med. (2010) In press :
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