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DHRS1 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q96LJ7 |
|---|---|
| Clone Names | 81006086 |
| Gene ID | 115817 |
|---|---|
| Other Names | Dehydrogenase/reductase SDR family member 1, 11--, DHRS1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | DHRS1 (HGNC:16445) |
|---|---|
| Synonyms | SDR19C1 |
| Function | NADPH-dependent oxidoreductase which catalyzes the reduction of steroids (estrone, androstene-3,17-dione and cortisone) as well as prostaglandin E1, isatin and xenobiotics in vitro (PubMed:30031147). May have a role in steroid and/or xenobiotic metabolism (PubMed:30031147). |
| Cellular Location | Endoplasmic reticulum. Note=May be attached to the ER membrane by its C-terminus segment. |
| Tissue Location | Detected in heart, liver, adrenal glands, and at low levels in skeletal muscle, kidney, pancreas and brain |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the short-chaindehydrogenases/reductases (SDR) family. The encoded enzyme containsa conserved catalytic domain and likely functions as anoxidoreductase. Multiple alternatively spliced variants, encodingthe same protein, have been identified.
References
Persson, B., et al. Chem. Biol. Interact. 178 (1-3), 94-98 (2009) :Wu, Q., et al. Mol. Biol. Rep. 28(4):193-198(2001)
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