|Other Names||3-hydroxyisobutyrate dehydrogenase, mitochondrial, HIBADH, HIBADH|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Tissue Location||Detected in skin fibroblasts.|
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Provided below are standard protocols that you may find useful for product applications.
3-hydroxyisobutyrate dehydrogenase(3-hydroxy-2-methylpropanoate:NAD(+) oxidoreductase, EC 22.214.171.124)is a dimeric mitochondrial enzyme that catalyzes theNAD(+)-dependent, reversible oxidation of 3-hydroxyisobutyrate, anintermediate of valine catabolism, to methylmalonatesemialdehyde.
Wheeler, H.E., et al. PLoS Genet. 5 (10), E1000685 (2009) :Rougraff, P.M., et al. J. Biol. Chem. 264(10):5899-5903(1989)Rougraff, P.M., et al. J. Biol. Chem. 263(1):327-331(1988)ROBINSON, W.G., et al. J. Biol. Chem. 225(1):511-521(1957)
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