|Other Names||Arf-GAP domain and FG repeat-containing protein 2, HIV-1 Rev-binding protein-like protein, Rev/Rex activation domain-binding protein related, RAB-R, AGFG2, HRBL, RABR|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
This gene is a member of the HIV-1 Rev binding protein(HRB) family and encodes a protein with one Arf-GAP zinc fingerdomain, several phe-gly (FG) motifs, and four asn-pro-phe (NPF)motifs. This protein interacts with Eps15 homology (EH) domains andplays a role in the Rev export pathway, which mediates thenucleocytoplasmic transfer of proteins and RNAs. Alternativelyspliced transcript variants have been described, but theirbiological validity has not been determined. The 3' UTR of thisgene contains an insulin receptor substrate 3-like pseudogene.
Doria, M., et al. J. Cell Biol. 147(7):1379-1384(1999)Glockner, G., et al. Genome Res. 8(10):1060-1073(1998)Salcini, A.E., et al. Genes Dev. 11(17):2239-2249(1997)Wong, W.T., et al. Proc. Natl. Acad. Sci. U.S.A. 92(21):9530-9534(1995)
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