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AGFG2 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | O95081 |
|---|---|
| Clone Names | 90819073 |
| Gene ID | 3268 |
|---|---|
| Other Names | Arf-GAP domain and FG repeat-containing protein 2, HIV-1 Rev-binding protein-like protein, Rev/Rex activation domain-binding protein related, RAB-R, AGFG2, HRBL, RABR |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | AGFG2 |
|---|---|
| Synonyms | HRBL, RABR |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene is a member of the HIV-1 Rev binding protein(HRB) family and encodes a protein with one Arf-GAP zinc fingerdomain, several phe-gly (FG) motifs, and four asn-pro-phe (NPF)motifs. This protein interacts with Eps15 homology (EH) domains andplays a role in the Rev export pathway, which mediates thenucleocytoplasmic transfer of proteins and RNAs. Alternativelyspliced transcript variants have been described, but theirbiological validity has not been determined. The 3' UTR of thisgene contains an insulin receptor substrate 3-like pseudogene.
References
Doria, M., et al. J. Cell Biol. 147(7):1379-1384(1999)Glockner, G., et al. Genome Res. 8(10):1060-1073(1998)Salcini, A.E., et al. Genes Dev. 11(17):2239-2249(1997)Wong, W.T., et al. Proc. Natl. Acad. Sci. U.S.A. 92(21):9530-9534(1995)
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