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PROSER1 Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q86XN7 |
|---|---|
| Clone Names | 90819049 |
| Gene ID | 80209 |
|---|---|
| Other Names | Proline and serine-rich protein 1, PROSER1, C13orf23, KIAA2032 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | PROSER1 (HGNC:20291) |
|---|---|
| Function | Mediates OGT interaction with and O-GlcNAcylation of TET2 to control TET2 stabilization at enhancers and CpG islands (CGIs). |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the ADAM (a disintegrin andmetalloprotease domain) family. Members of this family aremembrane-anchored proteins structurally related to snake venomdisintegrins, and have been implicated in a variety of biologicalprocesses involving cell-cell and cell-matrix interactions,including fertilization, muscle development, and neurogenesis. Theprotein encoded by this gene is highly expressed in testis and maybe involved in human spermatogenesis. Alternative splicing resultsin multiple transcript variants that encode the same protein.
References
Maloum, K., et al. Ann. Hematol. 88(12):1215-1221(2009)Oppezzo, P., et al. Blood 106(2):650-657(2005)Xu, R., et al. Genomics 62(3):537-539(1999)Cerretti, D.P., et al. Biochem. Biophys. Res. Commun. 263(3):810-815(1999)
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