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MARH3 Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q86UD3
Clone Names 91201332
Additional Information
Gene ID 115123
Other Names E3 ubiquitin-protein ligase MARCH3, 632-, Membrane-associated RING finger protein 3, Membrane-associated RING-CH protein III, MARCH-III, RING finger protein 173, MARCH3, RNF173
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MARCHF3 (HGNC:28728)
Synonyms MARCH3, RNF173
Function E3 ubiquitin-protein ligase which may be involved in endosomal trafficking. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
Cellular Location Cytoplasmic vesicle membrane; Multi-pass membrane protein. Early endosome membrane; Multi-pass membrane protein
Research Areas
Citations (0)
citation

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Background

MARCH3 is a member of the MARCH family of membrane-boundE3 ubiquitin ligases (EC 6.3.2.19). MARCH proteins add ubiquitin(see MIM 191339) to target lysines in substrate proteins, therebysignaling their vesicular transport between membrane compartments.MARCH3 appears to function in the endosomal recycling pathway(Fukuda et al., 2006 [PubMed 16428329]).

References

Fukuda, H., et al. J. Biochem. 139(1):137-145(2006)Bartee, E., et al. J. Virol. 78(3):1109-1120(2004)

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$ 277.78
Cat# BP17902b
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