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ITGA2 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P17301 |
|---|---|
| Clone Names | 100427123 |
| Gene ID | 3673 |
|---|---|
| Other Names | Integrin alpha-2, CD49 antigen-like family member B, Collagen receptor, Platelet membrane glycoprotein Ia, GPIa, VLA-2 subunit alpha, CD49b, ITGA2, CD49B |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | ITGA2 |
|---|---|
| Synonyms | CD49B |
| Function | Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. (Microbial infection) Integrin ITGA2:ITGB1 acts as a receptor for Human echoviruses 1 and 8. |
| Cellular Location | Membrane; Single-pass type I membrane protein. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene product belongs to the integrin alpha chainfamily. Integrins are heterodimeric integral membrane glycoproteinscomposed of a distinct alpha chain and a common beta chain. Theyare found on a wide variety of cell types including, T cells,fibroblasts and platelets. Integrins are involved in cell adhesionand also participate in cell-surface mediated signalling. [providedby RefSeq].
References
Nie, Y.M., et al. Transfus Med 20(6):376-382(2010)Motovska, Z., et al. Atherosclerosis 212(2):548-552(2010)Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Hozumi, K., et al. FEBS Lett. 584(15):3381-3385(2010)Wang, Y., et al. Diabet. Med. 27(4):376-383(2010)
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