|Other Names||DnaJ homolog subfamily B member 9, Endoplasmic reticulum DNA J domain-containing protein 4, ER-resident protein ERdj4, ERdj4, Microvascular endothelial differentiation gene 1 protein, Mdg-1, DNAJB9, MDG1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Involved in endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins. Acts as a co-chaperone with an Hsp70 protein.|
|Cellular Location||Endoplasmic reticulum lumen.|
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Provided below are standard protocols that you may find useful for product applications.
This gene is a member of the J protein family. J proteinsfunction in many cellular processes by regulating the ATPaseactivity of 70 kDa heat shock proteins. This gene is a member ofthe type 2 subgroup of DnaJ proteins. The encoded protein islocalized to the endoplasmic reticulum. This protein is induced byendoplasmic reticulum stress and plays a role in protectingstressed cells from apoptosis.
Zhang, H.M., et al. J. Virol. 84(17):8446-8459(2010)Lenna, S., et al. J. Immunol. 184(9):4654-4661(2010)McLaughlin, M., et al. J. Biol. Chem. 285(10):6960-6969(2010)Wang, M., et al. J. Biol. Chem. 284(48):33377-33383(2009)Colombo, F., et al. Int. J. Cancer 124(9):2179-2185(2009)
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