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MAEA Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q7L5Y9
Clone Names 110729133
Peptide ID 110729133
Additional Information
Gene ID 10296
Other Names Macrophage erythroblast attacher, Cell proliferation-inducing gene 5 protein, Erythroblast macrophage protein, Human lung cancer oncogene 10 protein, HLC-10, MAEA, EMP
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms EMP
Function Plays a role in erythroblast enucleation and in the development of the mature macrophages. Mediates the attachment of erythroid cell to mature macrophages, in correlation with the presence of MAEA at cell surface of mature macrophages; This MAEA- mediated contact inhibits erythroid cells apoptosis. Participates in erythroblastic island formation, which is the functional unit of definitive erythropoiesis. Associates with F-actin to regulate actin distribution in erythroblasts and macrophages. May contribute to nuclear architecture and cells division events.
Cellular Location Nucleus matrix. Cell membrane. Cytoplasm, cytoskeleton. Note=Localized as nuclear speckled- like pattern
Tissue Location Ubiquitous.
Research Areas
Citations (0)

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This gene product mediates the attachment of erythroblaststo macrophages. This attachment promotes terminal maturation andenucleation of erythroblasts, presumably by suppressing apoptosis.This protein is an integral membrane protein with the N-terminus onthe extracellular side and the C-terminus on the cytoplasmic sideof the cell. Two immunologically related isoforms of erythroblastmacrophage protein with apparent molecular weights of 33 kD and 36kD were detected in macrophage membranes; this gene encodes thelarger isoform. Multiple alternatively spliced transcript variantsencoding distinct isoforms have been found for this gene, but thebiological validity of some variants has not been determined.


Kobayashi, N., et al. Gene 396(2):236-247(2007)Bala, S., et al. Biochem. Biophys. Res. Commun. 342(4):1040-1048(2006)Hanspal, M., et al. Blood 92(8):2940-2950(1998)

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$ 80.00
Cat# BP17927a
Availability: In Stock
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