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TFAP2D Antibody (C-term) Blocking Peptide

Synthetic peptide

     
  • SPECIFICATION
  • CITATIONS
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Product Information
Primary Accession Q7Z6R9
Clone Names 110808294
Peptide ID 110808294
Additional Information
Gene ID 83741
Other Names Transcription factor AP-2-delta, AP2-delta, Activating enhancer-binding protein 2-delta, Transcription factor AP-2-beta-like 1, TFAP2D (HGNC:15581)
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TFAP2D (HGNC:15581)
Function Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC (By similarity).
Cellular Location Nucleus.
Tissue Location Highly expressed in brain, placenta, skeletal muscle, thymus, small intestine, and prostate, and expressed at lower levels in leukocyte, spleen, testis, ovary and colon. Barely detectable in heart, kidney, liver, lung or pancreas
Research Areas
Citations (0)

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Background

Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC (By similarity).

References

Kim, J.M., et al. DNA Res. 13(6):275-286(2006)Wenke, A.K., et al. Biochem. Biophys. Res. Commun. 345(1):495-501(2006)Cheng, C., et al. Int. J. Biochem. Cell Biol. 34(1):78-86(2002)

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$ 80.00
Cat# BP17936b
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