SEPT10 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9P0V9 |
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Clone Names | 110811002 |
Gene ID | 151011 |
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Other Names | Septin-10, SEPT10 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | SEPTIN10 (HGNC:14349) |
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Synonyms | SEPT10 |
Function | Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). |
Cellular Location | Cytoplasm. Cytoplasm, cytoskeleton. Cell projection, cilium, flagellum {ECO:0000250|UniProtKB:Q8C650}. Note=Detected in the annulus of the sperm flagellum and in the neck region in spermatids and mature sperm (By similarity). Using a GFP-fusion protein, detected in the nucleus. {ECO:0000250|UniProtKB:Q8C650, ECO:0000269|PubMed:12711328} |
Tissue Location | Widely expressed. Abundantly expressed in heart and kidney, placenta, skeletal muscles, liver and lung, as well as various tumor cell lines. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the septin family ofcytoskeletal proteins with GTPase activity. This protein localizesto the cytoplasm and nucleus and displays GTP-binding and GTPaseactivity. Alternate splicing results in two transcript variantsencoding different isoforms.
References
Benedetti, D., et al. Leukemia 22(1):224-226(2008)Lamesch, P., et al. Genomics 89(3):307-315(2007)Hillier, L.W., et al. Nature 434(7034):724-731(2005)Sui, L., et al. Biochem. Biophys. Res. Commun. 304(2):393-398(2003)
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