|Other Names||Septin-10, SEPT10|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential).|
|Cellular Location||Cytoplasm. Cytoplasm, cytoskeleton. Note=Using a GFP-fusion protein, detected in the nucleus.|
|Tissue Location||Widely expressed. Abundantly expressed in heart and kidney, placenta, skeletal muscles, liver and lung, as well as various tumor cell lines.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the septin family ofcytoskeletal proteins with GTPase activity. This protein localizesto the cytoplasm and nucleus and displays GTP-binding and GTPaseactivity. Alternate splicing results in two transcript variantsencoding different isoforms.
Benedetti, D., et al. Leukemia 22(1):224-226(2008)Lamesch, P., et al. Genomics 89(3):307-315(2007)Hillier, L.W., et al. Nature 434(7034):724-731(2005)Sui, L., et al. Biochem. Biophys. Res. Commun. 304(2):393-398(2003)
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