|Other Names||Coronin-1B, Coronin-2, CORO1B|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Regulates leading edge dynamics and cell motility in fibroblasts. May be involved in cytokinesis and signal transduction (By similarity).|
|Cellular Location||Cytoplasm, cytoskeleton. Note=Localized to the leading edge in fibroblasts, as well as weakly along actin stress fibers|
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Provided below are standard protocols that you may find useful for product applications.
Members of the coronin family, such as CORO1B, are WDrepeat-containing actin-binding proteins that regulate cellmotility (Cai et al., 2005 [PubMed 16027158]).
Cai, L., et al. Cell 128(5):915-929(2007)Cai, L., et al. J. Biol. Chem. 280(36):31913-31923(2005)Cai, L., et al. J. Biol. Chem. 280(36):31913-31923(2005)Parente, J.A. Jr., et al. J. Biol. Chem. 274(5):3017-3025(1999)Okumura, M., et al. DNA Cell Biol. 17(9):779-787(1998)
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