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CORO1B Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9BR76 |
|---|---|
| Clone Names | 110811049 |
| Gene ID | 57175 |
|---|---|
| Other Names | Coronin-1B, Coronin-2, CORO1B |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | CORO1B |
|---|---|
| Function | Regulates leading edge dynamics and cell motility in fibroblasts. May be involved in cytokinesis and signal transduction (By similarity). |
| Cellular Location | Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, stress fiber. Note=Localized to the leading edge in fibroblasts, as well as weakly along actin stress fibers |
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Provided below are standard protocols that you may find useful for product applications.
Background
Members of the coronin family, such as CORO1B, are WDrepeat-containing actin-binding proteins that regulate cellmotility (Cai et al., 2005 [PubMed 16027158]).
References
Cai, L., et al. Cell 128(5):915-929(2007)Cai, L., et al. J. Biol. Chem. 280(36):31913-31923(2005)Cai, L., et al. J. Biol. Chem. 280(36):31913-31923(2005)Parente, J.A. Jr., et al. J. Biol. Chem. 274(5):3017-3025(1999)Okumura, M., et al. DNA Cell Biol. 17(9):779-787(1998)
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