|Other Names||Intraflagellar transport protein 27 homolog, Putative GTP-binding protein RAY-like, Rab-like protein 4, IFT27, RABL4, RAYL|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Small GTPase-like component of the intraflagellar transport (IFT) complex B that promotes the exit of the BBSome complex from cilia via its interaction with ARL6 (PubMed:25443296). Not involved in entry of the BBSome complex into cilium. Prevents aggregation of GTP-free ARL6 (PubMed:25443296). Required for hedgehog signaling. Forms a subcomplex within the IFT complex B with IFT25 (By similarity).|
|Cellular Location||Cell projection, cilium|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a putative GTP-binding protein similarto RAY/RAB1C. The protein is ras-related, but the function isunknown. Several transcript variants encoding different isoformshave been found for this gene.
Qin, H., et al. Curr. Biol. 17(3):193-202(2007)Collins, J.E., et al. Genome Biol. 5 (10), R84 (2004) :Collins, J.E., et al. Genome Res. 13(1):27-36(2003)Dunham, I., et al. Nature 402(6761):489-495(1999)
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