|Other Names||Potassium voltage-gated channel subfamily F member 1, Voltage-gated potassium channel subunit Kv51, kH1, KCNF1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Putative voltage-gated potassium channel.|
|Cellular Location||Membrane; Multi-pass membrane protein.|
|Tissue Location||Detected in heart, brain, liver, skeletal muscle, kidney and pancreas|
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Voltage-gated potassium (Kv) channels represent the mostcomplex class of voltage-gated ion channels from both functionaland structural standpoints. Their diverse functions includeregulating neurotransmitter release, heart rate, insulin secretion,neuronal excitability, epithelial electrolyte transport, smoothmuscle contraction, and cell volume. This gene encodes a member ofthe potassium channel, voltage-gated, subfamily F. This gene isintronless and expressed in all tissues tested, including theheart, skeletal muscle, brain, kidney, and pancreas. [provided byRefSeq].
Cirulli, E.T., et al. Eur. J. Hum. Genet. 18(7):815-820(2010)Gutman, G.A., et al. Pharmacol. Rev. 57(4):473-508(2005)Ottschytsch, N., et al. Proc. Natl. Acad. Sci. U.S.A. 99(12):7986-7991(2002)Su, K., et al. Biochem. Biophys. Res. Commun. 241(3):675-681(1997)
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