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F2R Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P25116 |
|---|---|
| Clone Names | 91009035 |
| Gene ID | 2149 |
|---|---|
| Other Names | Proteinase-activated receptor 1, PAR-1, Coagulation factor II receptor, Thrombin receptor, F2R, CF2R, PAR1, TR |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | F2R |
|---|---|
| Synonyms | CF2R, PAR1, TR |
| Function | High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development. |
| Cellular Location | Cell membrane; Multi-pass membrane protein. |
| Tissue Location | Platelets and vascular endothelial cells. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Coagulation factor II receptor is a 7-transmembranereceptor involved in the regulation of thrombotic response.Proteolytic cleavage leads to the activation of the receptor. F2Ris a G-protein coupled receptor family member. [provided byRefSeq].
References
Bae, J.S., et al. J. Biol. Chem. 285(45):34803-34812(2010)Motovska, Z., et al. Atherosclerosis 212(2):548-552(2010)Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Burch, M.L., et al. J. Biol. Chem. 285(35):26798-26805(2010)Gigante, B., et al. PLoS ONE 5 (6), E11300 (2010) :
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