|Other Names||Proteinase-activated receptor 1, PAR-1, Coagulation factor II receptor, Thrombin receptor, F2R, CF2R, PAR1, TR|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||CF2R, PAR1, TR|
|Function||High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Platelets and vascular endothelial cells.|
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Provided below are standard protocols that you may find useful for product applications.
Coagulation factor II receptor is a 7-transmembranereceptor involved in the regulation of thrombotic response.Proteolytic cleavage leads to the activation of the receptor. F2Ris a G-protein coupled receptor family member. [provided byRefSeq].
Bae, J.S., et al. J. Biol. Chem. 285(45):34803-34812(2010)Motovska, Z., et al. Atherosclerosis 212(2):548-552(2010)Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Burch, M.L., et al. J. Biol. Chem. 285(35):26798-26805(2010)Gigante, B., et al. PLoS ONE 5 (6), E11300 (2010) :
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